Russ. J. Bioorganic Chem., 2021, 47(6):pages1352–1355

Conformationally Locked 5-Benzylidene-4H-Imidazolthion as a Fluorogenic Dye

We report novel conformationally locked 5-(4-(diethylamino)benzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazole-4-thion. Derivatives of conformationally locked chromophores of the fluorescentprotein containing sulfur instead of oxygen in the imidazolone fragment are characterized by red-shiftedspectra and higher extinction coefficient relative to the corresponding derivative containing an oxygen atom.That compound can be used as fluorogenic dyes for lipocalin-based fluorogen-activating proteins in fluorescent microscopy

Myasnyanko IN, Sycheva MA, Gavrikov AS, Baleeva NS, Baranov MS

Laboratory of chemistry of heterocyclic compounds

: 10.1134/S1068162021060200
Scopus: 2-s2.0-85121439516
IBCH: 9644
Ссылка на статью в журнале: https://link.springer.com/article/10.1134/S1068162021060200
Кол-во цитирований на 09.2024: 0
Данные статьи проверены модераторами 2021-12-20

Список научных проектов, где отмечена публикация

  1. -Разработка новых молекулярных инструментов ферментативного и флуорогенного флуоресцентного мечения для прижизненной визуализации в живых системах (July 1, 2018 — June 30, 2023). Baranov M.S., Baleeva N.S., Goncharuk S.A., Myasnyanko I.N., Smirnov A.Y.. Grant, RSF.