Russ. J. Bioorganic Chem., 2021, 47(1):334-337

Styrene Derivatives of Indole and Pyranone as Fluorogenic Substrates for FAST Protein

We report novel styrene derivatives of indole and pyranone. The possibility of their use as fluorogens for FAST protein were investigated. Derivatives of indole do not exhibit noticeable fluorogenic properties, while derivatives of pyranone exhibit superior fluorogenic potential; binding to a protein leads to an increase in fluorescence intensity and a emission red shift.

Sokolov AI, Myasnyanko IN, Baleeva NS, Baranov MS

Laboratory of chemistry of heterocyclic compounds

: 10.1134/S1068162021010234
Scopus: 2-s2.0-85102749203
IBCH: 9156
Ссылка на статью в журнале: http://link.springer.com/10.1134/S1068162021010234
Кол-во цитирований на 05.2024: 1
Данные статьи проверены модераторами 2021-04-03

Список научных проектов, где отмечена публикация

  1. -Разработка новых молекулярных инструментов ферментативного и флуорогенного флуоресцентного мечения для прижизненной визуализации в живых системах (July 1, 2018 — June 30, 2023). Baranov M.S., Baleeva N.S., Goncharuk S.A., Myasnyanko I.N., Smirnov A.Y.. Grant, RSF.