-Низкомолекулярные модуляторы сплайсинга РНК нового поколения как потенциальные препараты для терапии глиобластомы человека

January 6, 2022 — December 31, 2024

Shahparonov M.I. (PI)

Laboratory of membrane bioenergetics

Grant, RSF

List of publications

  1. Larionova TD, Bastola S, Aksinina TE, Anufrieva KS, Wang J, Shender VO, Andreev DE, Kovalenko TF, Arapidi GP, Shnaider PV, Kazakova AN, Latyshev YA, Tatarskiy VV, Shtil AA, Moreau P, Giraud F, Li C, Wang Y, Rubtsova MP, Dontsova OA, Condro M, Ellingson BM, Shakhparonov MI, Kornblum HI, Nakano I, Pavlyukov MS (2022). Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells. Nat Cell Biol 24 (10), 1541–1557
  2. Kovalenko TF, Yadav B, Anufrieva KS, Larionova TD, Aksinina TE, Latyshev YA, Bastola S, Shakhparonov MI, Pandey AK, Pavlyukov MS (2023). PTEN regulates expression of its pseudogene in glioblastoma cells in DNA methylation-dependent manner. Biochimie 219, 74–83
  3. Isakova AA, Artykov AA, Plotnikova EA, Trunova GV, Khokhlova VА, Pankratov AA, Shuvalova ML, Mazur DV, Antipova NV, Shakhparonov MI, Dolgikh DA, Kirpichnikov MP, Gasparian ME, Yagolovich AV (2023). Dual targeting of DR5 and VEGFR2 molecular pathways by multivalent fusion protein significantly suppresses tumor growth and angiogenesis. Int J Biol Macromol 255, 128096
  4. Borisevich SS, Aksinina TE, Ilyina MG, Shender VO, Anufrieva KS, Arapidi GP, Antipova NV, Anizon F, Esvan YJ, Giraud F, Tatarskiy VV, Moreau P, Shakhparonov MI, Pavlyukov MS, Shtil AA (2024). The Nitro Group Reshapes the Effects of Pyrido[3,4-g]quinazoline Derivatives on DYRK/CLK Activity and RNA Splicing in Glioblastoma Cells. Cancers (Basel) 16 (4),
  5. Levakov SA, Gromova TA, Mamedova AE, Antipova NV (2024). New perspectives in searching diagnostic markers for ovarian endometriosis. Akush Ginekol (Mosk) 2024 (1), 110–116
  6. Shender VO, Anufrieva KS, Shnaider PV, Arapidi GP, Pavlyukov MS, Ivanova OM, Malyants IK, Stepanov GA, Zhuravlev E, Ziganshin RH, Butenko IO, Bukato ON, Klimina KM, Veselovsky VA, Grigorieva TV, Malanin SY, Aleshikova OI, Slonov AV, Babaeva NA, Ashrafyan LA, Khomyakova E, Evtushenko EG, Lukina MM, Wang Z, Silantiev AS, Nushtaeva AA, Kharlampieva DD, Lazarev VN, Lashkin AI, Arzumanyan LK, Petrushanko IY, Makarov AA, Lebedeva OS, Bogomazova AN, Lagarkova MA, Govorun VM (2024). Therapy-induced secretion of spliceosomal components mediates pro-survival crosstalk between ovarian cancer cells. Nat Commun 15 (1), 5237
  7. Levakov SA, Pertseva YA, Kaviladze MG, Gromova TA, Chernyshenko TA, Gondarenko EA, Mazur DV, Mishanova AV, Shakhparonov MI, Mashtagova KM, Antipova NV (2023). Evaluation of expression patterns of different nicotinic acetylcholine receptor subunits in ovarian endometriosis in the search for promising new therapeutic targets for endometriosis. Voprosy Ginekologii, Akusherstva i Perinatologii 22 (5), 5–14