Education
Period |
Coyntry, city |
University |
Additional info |
1998–2003 |
Russia, Moscow |
Dept. of Biophysics, Faculty of Biological Sciences M.V. Lomonosov State University |
with honor |
IBCh positions
Titles
|
Doctor of Philosophy (Physico-mathematical sciences) |
Scientific interests
My major interests are: 1) organization of biomolecular surfaces, 2) principles of polypeptide chain folding in different environments (water, water-lipid interface, membrane etc.), 3) mechanisms of protein oligomerization in the membrane medium, 4) protein-membrane and protein-RNA interactions, and 5) design of novel drugs, which have specific membrane targets.
In my research I use combined molecular modeling approaches. Among them are:
- coarse-grained and atomistic computer simulations of proteins, peptides and drugs in explicit solvents and membrane systems (molecular dynamics, free energy estimation etc.);
- molecular hydrophobicity potential calculations and surface analysis of biomolecules;
- bioinformatics analysis of protein and RNA sequences.