-Моно- и полиферментные системы как основной инструмент в создании новых фармацевтически значимых модифицированных нуклеозидов и нуклеотидов

List of publications

1. Abramchik Y, Zayats E, Kostromina M, Lykoshin D, Fateev I, Konstantinova I, Zhukhlistova N, Timofeev V, Kuranova I, Esipov R (2021). Comparison of spatial structures and packaging of phosphorybosil pyrophosphate synthetase 2 from thermus thermophilus hb27 in rhombohedral and tetragonal crystals. Crystals (Basel) 11 (9),
2. Berzina MY, Eletskaya BZ, Kayushin AL, Dorofeeva EV, Lutonina OI, Fateev IV, Paramonov AS, Kostromina MA, Zayats EA, Abramchik YA, Maltsev DV, Naumenko LV, Taran AS, Yakovlev DS, Spasov AA, Miroshnikov AI, Esipov RS, Konstantinova ID (2022). Synthesis of 2-chloropurine ribosides with chiral amino acid amides at C6 and their evaluation as A1 adenosine receptor agonists. Bioorg Chem 126, 105878
3. Konstantinova ID, Andronova VL, Fateev IV, Esipov RS (2022). Favipiravir and Its Structural Analogs: Antiviral Activity and Synthesis Methods. Acta Naturae 14 (2), 16–38
4. Zayats EA, Fateev IV, Kostromina MA, Abramchik YA, Lykoshin DD, Yurovskaya DO, Timofeev VI, Berzina MY, Eletskaya BZ, Konstantinova ID, Esipov RS (2022). Rational Mutagenesis in the Lid Domain of Ribokinase from E. coli Results in an Order of Magnitude Increase in Activity towards D-arabinose. Int J Mol Sci 23 (20),
5. (conference) Арнаутова АО, Константинова ИД, Каюшин АЛ, Антонов КВ (2022). New method of chemoenzymatic synthesis of 2- fluorocordycepin. Nucleosides Nucleotides Nucleic Acids ,
6. Smirnova OS, Berzina MY, Fateev IV, Eletskaya BZ, Kostromina MA, Kayushin AL, Paramonov AS, Prutkov AN, Grebenkina LE, Chudinov MV, Andronova VL, Galegov GA, Deryabin PG, Miroshnikov AI, Esipov RS, Konstantinova ID (2022). Chemo-enzymatic synthesis of 5-substituted ribavirin analogs: Unexpected cooperative effect in the interaction of 5-alkyloxymethyl 1,2,4-triazol-3-carboxamides with E. coli purine nucleoside phosphorylase active site. Sustainable Chemistry and Pharmacy 30, 100881
7. Abramchik YA, Timofeev VI, Zhukhlistova NE, Shevtsov MB, Fateev IV, Kostromina MA, Zayats EA, Kuranova IP, Esipov RS (2022). Crystallization and Preliminary X-Ray Diffraction Analysis of Recombinant Phosphoribosylpyrophosphate Synthetase I from Thermus thermophilus HB27. Cryst. Rep 67 (4), pages 586–589
8. Khandazhinskaya A, Fateev I, Eletskaya B, Maslova A, Konstantinova I, Seley-Radtke K, Kochetkov S, Matyugina E (2023). Design and Synthesis of New Modified Flexible Purine Bases as Potential Inhibitors of Human PNP. Molecules 28 (3), 928
9. Eletskaya BZ, Berzina MY, Fateev IV, Kayushin AL, Dorofeeva EV, Lutonina OI, Zorina EA, Antonov KV, Paramonov AS, Muzyka IS, Zhukova OS, Kiselevskiy MV, Miroshnikov AI, Esipov RS, Konstantinova ID (2023). Enzymatic Synthesis of 2-Chloropurine Arabinonucleosides with Chiral Amino Acid Amides at the C6 Position and an Evaluation of Antiproliferative Activity In Vitro. Int J Mol Sci 24 (7), 6223
10. Berzina MY, Eletskaya BZ, Kayushin AL, Dorofeeva EV, Lutonina OI, Fateev IV, Zhavoronkova ON, Bashorin AR, Arnautova AO, Smirnova OS, Antonov KV, Paramonov AS, Dubinnyi MA, Esipov RS, Miroshnikov AI, Konstantinova ID (2023). Intramolecular Hydrogen Bonding in N6-Substituted 2-Chloroadenosines: Evidence from NMR Spectroscopy. Int J Mol Sci 24 (11), 9697
11. Garipov IF, Timofeev VI, Zayats EA, Abramchik YA, Kostromina MA, Konstantinova ID, Esipov RS (2023). Structural Bioinformatics Study of the Structural Basis of Substrate Specificity of Purine Nucleoside Phosphorylase from Thermus thermophilus. Cryst. Rep 68 (2), 280–287
12. Abramchik YA, Zayats EA, Timofeev VI, Shevtsov MB, Kostromina MA, Fateev IV, Yurovskaya DO, Karanov AA, Konstantinova ID, Kuranova IP, Esipov RS (2023). Preliminary X-ray Study of Crystals Obtained by Co-Crystallization of Hypoxanthine‒Guanine Phosphoribosyltransferase from Escherichia coli and Pyrazine-2-Carboxamide Derivatives. Cryst. Rep 68 (6), 852–856