International Conference on Biomolecular Science in honor of Professor Yuri A. OVCHINNIKOV

PROGRAMM OF THE CONFERENCE:

 
Monday, September 28

Large Conference Hall, Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow

10.00-10.30   Welcome Ceremony

V.T. Ivanov (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia)
Introductory Remarks 
10.30-11.00 J. Walker (The Nobel Prize in Chemistry 1997, the MRC Mitochondrial Biology Unit, Cambridge, UK)
How ATP is made
11.00-11.20 N.N. Modyanov (University of Toledo, USA) 
BetaM - an enigmatic member of Na,K-ATPase beta-subunit family
12.00-12.20 M.V. Kovalchuk (RRC Kurchatov Institute and Shubnikov Institute of Crystallography, RAS, Moscow, Russia)
Convergence of technologies and sciences as a basis for a new technological trend
12.20-12.40 E. Carafoli (University of Padova, Italy)
Calcium signaling: a meeting point for cellular and structural biochemistry
12.40-13.00 A.S. Spirin (Institute of Protein Research, RAS, Pushchino, Russia)
Protein-synthesizing machine of the cell
13.00-13.20
A.A. Bogdanov (Belozersky Institute of Physicochemical Biology, MSU, Moscow, Russia)
Contribution of the ribosomal tunnel in regulation of translation: the structural insight
14.20-14.40 E.V. Grishin (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia)
Structural and functional diversity of natural venoms
14.40-15.00 S. Papa (University of Bari, Italy)
Molecular regulation of cellular respiration: from protein allosteric cooperativity to post-translational modification
15.00-15.20 R. Glockshuber (Institute of Molecular Biology and Biophysics, ETH Zurich, Switzerland) 
Assembly of adhesive type 1 pili from Escherichia coli
15.40-16.00 F. Hucho (Freie Universität Berlin, Germany) 
25 Years of receptor research, 25 years of cooperation
16.00-16.20 V.I. Tsetlin (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia)
Peptide and protein neurotoxins in studies on nicotinic receptors
16.20-16.40 J. Tombran-Tink (Pennsylvania State University College of Medicine, Hershey, PA, USA)
PEDF determines risk in neurodegenerative diseases
16.40-17.00 C.J. Barnstable (Pennsylvania State University College of Medicine, Hershey, PA, USA)
Signal pathways that regulate both neural development and degeneration

17.00-19.00 Young Scientists Competition


Tuesday, September 29 
 

Small Conference Hall, Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow

 

Chairmen: V.P.Skulachev, J. Walker

 

10.00-10.30  K.Wuthrich    (The Nobel Prize in Chemistry 2002; The Scripps Research Institute, La Jolla, CA, USA and ETH Zurich, Zurich, Switzerland) 

 “From Structural Biology to Structural Genomics: The Expanding Protein Universe”

10.30-10.50 V.A. Shuvalov (Institute of Fundamental Problems of Biology, Pushchino, Russia)

“Femtosecond light energy conversion in bacterial reaction centers”

10.50-11.10 J. Puglisi (Stanford University School of Medicine, USA)

"Dynamics of translation"

11.10-11.30 Yu.A. Chizmadzhev (Frumkin Institute of Physical Chemistry and Electrochemistry, Moscow, Russia)

“Nanodomains (rafts) in model and cell membranes: theoretical study”

11.30-11.50 A.S. Arseniev (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Structural biology of transmembrane helix-helix interaction”                                                  

 

11.50-12.10 Coffee Break

 

Chairmen: T.V. Ovchinnikova, H.G. Sahl

 

12.10-12.30 V.A. Tkachuk  (Moscow State University and  Cardiology Research Center, Moscow, Russia)

“Molecular mechanisms of blood vessels growth and remodelling”

12.30-12.50 M. Cortijo (Universidad Complutense de Madrid, Spain)

“The role of the rostral anterior cingulated cortex in the detection of novel conflicts”

12.50-13.10 M.A. Ostrovsky (Emanuel Institute of Biochemical Physics, Russia)

“Peculiarities of the first and last stages of visual pigment rhodopsin photolysis”

13.10-13.30 N.G. Abdulaev (University of Maryland, USA)

"Direct observation of structural  coupling between rhodopsin and transducin"

 

13.30-14.30 Lunch

 

Chairmen: R.V. Petrov, M. Sela

 

14.30-14.50 M. Sela (The Weizmann Institute of Science, Rehovot, Israel)

"Towards therapeutic vaccines against autoimmune diseases and cancer”

14.50-15.10 A.G.Gabibov  (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Artificial enzymes and catalytic vaccines”

15.10-15.30  S.M.Deev (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Recombinant anticancer immunotoxins”

15.30-15.50 N.V.Bovin (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

"Natural antibodies against glycans: facts and hypotheses"

 

15.50-16.10  Coffee Break

 

Chairmen: M. Cortijo, E.D. Sverdlov

 

16.10-16.40 A. Ciechanover (The Nobel Prize in Chemistry 2004, Vascular and Tumor Biology Research Center, Haifa, Israel)

“Why our proteins have to die so we shall live”

16.40-17.00  V.P. Skulachev (Belozersky Institute of Physicochemical Biology, Moscow, Russia)

"A mitochondria-targeted plastoquinone derivative as a tool to interrupt senescence program"

17.00-17.20  H.G. Sahl (Pharmaceutical Microbiology, University of Bonn, Germany)

“Cationic host defence peptides – how do they kill microbes?”

17.20-17.40  S.A. Nedospasov (Engelhardt Institute of Molecular Biology, Moscow, Russia)

“Mediators of innate immunity”

 

17.40 Cultural program

 

Wednesday, September 30

 

09.00  Departure to Pushchino

 

Conference Hall, Pushchino branch of Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Pushchino

 

Chairmen: A.I. Miroshnikov, S. Reissmann

 

11.00-11.20 V.P. Zubov (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Bioanalytical reagents based on polymer-encapsulated fluorescent semiconductor CdSe(ZnS) nanocrystals”

11.20-11.40 A.V. Finkelstein (Institute of Protein Research, Pushchino, Russia)

“Protein folding: dependence on size, shape, structure and stability of the protein”

11.40-12.00 S. Lutsenko (Department of Biochemistry and Molecular Biology, Oregon Health and Science University, USA)

“Understanding liver pathology using biochemistry and biophysics toolkit”

12.00-12.20 K. Petrukhin (Columbia University, USA)  

"Fighting blindness: from gene discoveries to drug development"

 

 

12.20-12.40 – Coffee break

 

Chairmen: R.G.Efremov,  J. Puglisi  

 

12.40-13.00 V.V. Bezuglov (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“N-Acyldopamines – multifunctional lipid regulators”

13.00-13.20 L. B.-A. Johansson (Umeå Universitet, Sweden)

“Electronic energy transfer/migration and biomacromolecular structure”

13.20-13.40 E.L. Vodovozova (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Effective anticancer liposomes bearing lipophilic prodrugs and carbohydrate ligands”

 

13.40-14.40 – Lunch

 

Chairmen: V.M. Lipkin,  J. Tombran-Tink

 

14.40-15.00  C. Vinson (National Cancer Institute at Bethesda, USA)

“Methyl CpG and Differentiation”

15.00-15.20G.V. Shpakovsky (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“POLR2J and PMS2 gene families as molecular markers of higher primates evolution”

15.20-15.40 M. Vigneron (Ecole Superieure de Biotechnologie de Strasbourg, France)

“RNA polymerases in parasitic protozoan”

 

15.40-16.00 – Coffee break

 

16.00 Departure to Moscow. Cultural program

 

Thursday, October 1

 

Small Conference Hall, Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow

Chairmen: A. Azzi, M.P. Kirpichnikov

 

10.00-10.20 K.G. Skryabin (Centre “Bioengineering”, RRC Kurchatov Institute, Moscow, Russia)

“Functional genomics: from Archaea to Homo sapiens”

10.20-10.40 J. Diaz (Centre Léon Bérard, CNRS-UCBL, Lyon, France)

 ”A proteomic view of viral infection and tumor progression: the ribosome, a key player?”

10.40-11.00 V.M. Govorun (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Comparative proteomics of mycoplasm”

11.00-11.20 A. Tossi (University of Trieste, Italy)

“Helical antimicrobial and host defense peptides – lessons from design and evolution”

 

11.20-11.40 Coffee Break

 

Chairmen: V.I Tsetlin, C. Vinson

 

11.40-12.00 T.M. Andronova, V.T. Ivanov  (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“GMDP story: from Mechnikov’s ideas to NOD-2 receptor ligands”

12.00-12.20 A.G. Petrenko (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Orphan receptor-like tyrosine kinase as an alkali sensor”

12.20-12.40 O.Yu. Chertov (Protein Chemistry Laboratory SAIC-Frederick, USA)

“Analytical protein chemistry in modern biomedical research”

12.40-13.00 T. Haertle (Institut National de la Recherche Agronomique, Nantes, France)

“Engineering of caseins and the modulation of their chaperone like properties and immunoreactivities”

 

13.00-14.00 Lunch

 

Chairmen: J.-J. Diaz, A.G. Gabibov

 

14.00-14.20 D.G. Knorre (Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia)

“Antisense approach. History and present state”

14.20-14.40 V.A. Efimov (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“Synthetic oligonucleotides, their analogues and conjugates: synthesis,  properties and applications”

14.40-15.00 E.D. Sverdlov (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia)

“What makes us human? Human endogenous retroviruses?”

15.00-15.20 S.N. Kochetkov (Engelhardt Institute of Molecular Biology, Moscow, Russia)

"Interactions of HCV proteins with viral and host components"

15.20-15.40 E.N. Chertova (Protein Chemistry Laboratory SAIC-Frederick, USA)

“Envelope glycoprotein on HIV and SIV virions: biochemical and electron tomography analysis”

 

15.40-16.00 Coffee Break

 

Chairmen: E.V. Grishin, F. Hucho

 

16.00-16.20 S. Reissmann (Institute of Biochemistry and Biophysics, Germany)

“High yield internalization of peptides, proteins and nucleotides into different cells by cell penetrating peptides”

16.20-16.40  E.S. Severin (Research Centre for Molecular Diagnostics & Therapy, Moscow, Russia)

“Pyridoxal catalysis, сАМР-dependent proteinkinase and membrane receptor systems (50 years of cooperation)”

16.40-17.00  A. Azzi (Vascular Biology Laboratory, Boston, USA)

"Alpha-Tocopherol, from antioxidant vitamin to gene expression regulator”

17.00-17.20 R.G. Vasilov (Russian Society of Biotechnologists, Moscow, Russia)

Young Scientists Competition: Award Ceremony.

17.20-17.40 T.V. Ovchinnikova (Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia). Closing remarks.
 

september 27, 2009