Institute of
bioorganic chemistry

Researchers from the Laboratory of Cell Interactions, IBCh RAS, together with colleagues from the Department of Immunology and the Department of Bioengineering of Moscow State University, in their work “HSP70 Multi-Functionality in Cancer” examined various functions of HSP70 in the Hallmarks of Cancer. This work emphasizes the importance of understanding the structure, functional cycle, conformational changes of HSP70 for the future development of effective anticancer therapy. Using molecular docking studies, the interaction of key HSP70 domains with various receptors has also been demonstrated. The work was published in Cells.