Institute of
bioorganic chemistry

Plant lignans are active components of many herbs, which makes them the research objects for therapeutic agents development for practical use. They provide diverse naturally-occurring pharmacophores, which allows them to interact with various enzymes, receptors, ion channels and signaling molecules. A team of scientists from IBCh RAS published a review that summarizes the comprehensive knowledge about lignan use as a bioactive compounds in disorders associated with oxidative stress and inflammation, pharmacological effects in vitro and in vivo, molecular mechanisms underlying these effects, and chemical synthesis approaches. The work is published in the International Journal of Molecular Sciences. Learn more