Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers
The scientists from the Laboratory of biocatalysis, the Laboratory of proteolytic enzyme chemistry, the Laboratory of bioinformatics approaches in combinatorial chemistry and biology and the Laboratory of hormonal regulation proteins, together with colleagues from EMBL-Hamburg, Moscow State University. M.V. Lomonosov, the Sheffield Institute and the Scripps Research Institute have developed a universal algorithm that makes it possible to create biological antidotes based on biocatalysts, directionally increasing their reactivity, and to predict stereoselectivity. The work was published in the journal Proceedings of the National Academy of Sciences. Learn more
september 10, 2020